VSoothe 2 Vaginal Cream

VSoothe 2 Vaginal Cream is a compounded preparation, made to the strength and directions your prescriber specifies. Prepared in: Cyclobenzaprine HCl / Gabapentin / Ketamine / Lidocaine 3/5/5/5% 30 mL Topi-Click PERL Dispenser.

Prescribers order preparations of this kind for conditions affecting the vulva and vagina, where placing medicine directly at the site suits better than a tablet.

All of our compounding is done at Brandon Pharmacy and Compounding and transferred to our other four Florida stores, so you can collect it wherever you normally go. A prescription is required. Compounded preparations are not FDA-approved.

• Cyclobenzaprine 3% — a muscle relaxant, included where muscle spasm forms part of the pain.
• Gabapentin 5% — used for nerve-related pain, the kind described as burning, shooting or hypersensitive.
• Ketamine 5% — at these topical concentrations, included for its action on NMDA receptors involved in persistent pain signalling.
• Lidocaine 5% — a local anesthetic that numbs the tissue it is applied to by blocking nerve signals.

Apply the amount your prescriber has specified, using the measured applicator, to the area they have indicated. Directions vary between patients, so follow the label on your tube rather than any general guidance.

If you miss a dose, apply it when you remember, unless it is nearly time for the next one. Do not apply extra to catch up.

Wash your hands after applying, and keep the cream away from your eyes and mouth.

These ingredients can be absorbed into the bloodstream even though the cream is applied locally, so interactions with medicines taken by mouth are possible. Give your pharmacist a complete list of what you take, including anything bought without a prescription.

• Cyclobenzaprine should not be combined with MAO inhibitors. Alcohol, barbiturates and benzodiazepines add to its sedative effect.
• Gabapentin absorption is reduced by magnesium- and aluminium-containing antacids; combined with opioids it can increase sedation and slow breathing.
• Ketamine adds to the effect of other sedatives and anesthetics.
• Lidocaine can interact with other local anesthetics and with some heart medicines, affecting heart rate and blood pressure.

Tell your prescriber if you are pregnant, planning a pregnancy or breastfeeding.

The most common effect is local: irritation, redness, stinging or discomfort where the cream is applied. Each of the ingredients can also cause effects of its own, and because some absorption occurs these are not limited to the application site.

Stop using it and contact a pharmacist or your prescriber if you develop a rash, significant swelling, drowsiness, dizziness, confusion, a change in heart rate, or any symptom that concerns you.

VSoothe 2 Vaginal Cream is compounded at Brandon Pharmacy and Compounding and transferred to our other stores, so you can collect it at whichever is closest to you: Cape Coral, Fort Myers, Brandon or Riverview. Local delivery is free.