Low dose naltrexone (LDN)

Low dose naltrexone is prescribed at strengths between about 0.5 mg and 4.5 mg. Commercial naltrexone is made at 50 mg, so the low doses have to be compounded.

What we prepare

  • LDN capsules at the exact strength prescribed
  • Slow titration sets, where a prescriber wants to build the dose gradually
  • Capsules in a filler suited to patients who react to lactose
  • Liquid preparations where a capsule is unsuitable

Low dose naltrexone is prescribed for a range of conditions. Whether it is appropriate for you is a decision for your prescriber, not for us — what we can do is prepare it accurately once they have decided.

Everything on this page is prepared to a prescriber’s order for one named patient. We cannot prepare or supply any of it without a valid prescription.

Why LDN has to be compounded

Naltrexone is manufactured as a 50 mg tablet. “Low dose” prescribing calls for a small fraction of that — typically a few milligrams — which no manufacturer produces. Compounding is the only way to dispense it accurately at that strength.

LDN is prescribed off-label. That means a prescriber is using an approved drug for a purpose outside its approved labelling, which is lawful and common, but it does mean the evidence base differs from an approved indication. Ask your prescriber what they expect it to do and how you will both judge whether it is working.

How a compounded prescription works here

  • Your prescriber decides. They specify the drug, the strength, the base and the form. We do not choose your treatment and we cannot start one.
  • We confirm with you — what it will cost, how long it takes, and anything you need to know about storage or use.
  • We compound it at our Brandon facility and send it to whichever of our pharmacies you use.
  • You collect it, or we deliver free.

A valid prescription is required, and we dispense to patients in Florida only. Compounded preparations are not approved by the U.S. Food and Drug Administration, and the FDA does not review them for safety, effectiveness or quality. The preparations named on this page describe what we can make — they are not claims that any of them is proven to treat a condition, and nothing here is a recommendation to use a particular medicine.

Browse everything we compound in the drug catalog, or talk to one of our pharmacists — no charge, no obligation, and we will tell you if we think compounding is not the answer.